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Methyltestosterone can promote the male sex organs and used in seedling stage sex change. Methyltestosterone is a steroid hormone from the androgen and is found in mammals and other vertebrates, Methyltestosterone is primarily secreted in the tests of mails and the ovaries of female, although small amount are also secreted by the adrenal glands, Methyltestosterone is the principle male sex hormone and an anabolic steroid.
Methyltestosterone plays a key role in the development of male reproductive tissue such as the testis and prostates. In addition, Methyltestosterone is essential for health and well-being as well as the prevention of osteoporosis, Methyltestosterone is conserved through most vertebrates, although fish make a slightly difference from called 11-ketotestosterone.
Buy Methyltestosterone Online. A synthetic anabolic steroid used for treating men with testosterone deficiency or similar androgen replacement therapies. Also, has antineoplastic properties and so has been used secondarily in women with advanced breast cancer. Methyltestosterone is a schedule III drug in the US.
Indication
Methyltestosterone is an anabolic steroid hormone use to treat men with a testosterone deficiency. It is also use in women to treat breast cancer, breast pain, swelling due to pregnancy, and with the addition of estrogen it can treat symptoms of menopause.
Pharmacodynamics
Testosterone is a steroid hormone from the androgen group. Testosterone is primarily secret from the testes of males. It is the principal male sex hormone and an anabolic steroid. In both males and females, it plays key roles in health and well-being. Examples include enhanced libido, energy, immune function, and protection against osteoporosis. On average, the adult male body produces about twenty times the amount of testosterone than an adult female’s body does.
The effects of testosterone in humans and other vertebrates occur by way of two main mechanisms: by activation of the androgen receptor (directly or as DHT), and by conversion to estradiol and activation of certain estrogen receptors. Free testosterone (T) is transportable into the cytoplasm of target tissue cells, where it can bind to the androgen receptor, or can be reduce to 5α-dihydrotestosterone (DHT) by the cytoplasmic enzyme 5α-reductase.
DHT binds to the same androgen receptor even more strongly than T, so that its androgenic potency is about 2.5 times that of T. The T-receptor or DHT-receptor complex undergoes a structural change that allows it to move into the cell nucleus and bind directly to specific nucleotide sequences of the chromosomal DNA. The areas of binding are call hormone response elements (HREs), and influence transcriptional activity of certain genes, producing the androgen effects.
Absorption
The methyl group aids to increase oral bioavailability.
Protein binding 40% of testosterone in plasma is bound to sex hormone-binding globulin and 2% remains unbound and the rest is bound to albumin and other proteins. Buy Methyltestosterone Online.
Metabolism
Hepatic. Testosterone is metabolized to 17-keto steroids through two different pathways. The major active metabolites are estradiol and dihydrotestosterone (DHT).
Route of elimination
90% urine / 10% feces
Half-life
6-8 hours
| Grams | 50, 100, 20 |
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